Cabergoline: Uses, Interactions, Mechanism of Action DrugBank Online

Use ofDOSTINEX for the inhibition or suppression of physiologic lactation is notrecommended (see PRECAUTIONS section). For the treatment of hyperprolactinemic disorders, either idiopathic or due to prolactinoma (prolactin-secreting adenomas). May also be used to manage symptoms of Parkinsonian Syndrome as monotherapy during initial symptomatic management or as an adjunct to levodopa therapy during advanced stages of disease. This medicine belongs to a group of medicines called dopamine agonists.

Follow all instructions from your doctor and pharmacist carefully. It is recommended that women who plan to become pregnant stop taking Cabaser at least one month before becoming pregnant. Check with your doctor right away if you have symptoms of fainting, hallucinations (seeing, hearing, or feeling things that are not there), lightheadedness, stuffy nose, or racing heartbeat.

Dose advice: How to use Cabaser

The following interactions have been selected on the basis of their potential significance and are not necessarily all-inclusive. Using cabergoline with other drugs that make you drowsy can worsen this effect. Ask your doctor before using opioid medication, a sleeping pill, a muscle relaxer, or medicine for anxiety or seizures. This is not a complete list of side effects and others may occur.

Of Interest This Week

In medical circles it is commonly used to combat prolactinomas, a benign tumor of the pituitary gland that may cause an excess production of prolactin. It is also used by athletes who supplement with anabolic steroids that may increase prolactin levels such as Nandrolone and Trenbolone. The concomitant use of antiparkinson non-dopamine agonists (e.g. selegiline, amantadine, biperiden, trihexyphenidyl) was allowed in clinical studies for patients receiving cabergoline. In https://www.classicalkidsnfp.org/nebido-how-to-buy-2/ studies where the pharmacokinetic interactions of cabergoline with L-dopa or selegiline were evaluated, no interactions were observed. In 72 healthy volunteers,single or multiple doses (up to 2 mg) of cabergoline resulted in selectiveinhibition of prolactin with no apparent effect on other anterior pituitaryhormones (GH, FSH, LH, ACTH, and TSH) or cortisol.

• Food does not appear to affect absorption and disposition of cabergoline.
• [Major] The use of cabergoline is contraindicated in patients with uncontrolled hypertension.
• Before starting treatment with Cabaser your doctor will need to do some tests, to detect any underlying heart, lung or kidney disease.
• The higher the dose of Cabaser, the more likely it will cause a fall in your blood pressure.
• The recommended dosage of Cabaser tablets for initiation of therapy is 0.25 mg twice a week.
• You are encouraged to report negative side effects of prescription drugs to the FDA.

Food Interaction

You should not take more than 3 mg of this medicine in one day. The usual starting dose of Cabaser is 1 mg daily, preferably taken after food to reduce the side-effects. For the management of the signs and symptoms of Parkinson’s disease.Treatment should be initiated under specialist supervision. Cabaser belongs to a group of medicines called dopamine agonists. Symptoms of overdose would likely be those of over-stimulation of dopamine receptors, e.g. nausea, vomiting, gastric complaints, postural hypotension, confusion/psychosis or hallucinations. Clinical diagnostic monitoring for development of fibrotic disorders, as appropriate, is essential.

This is usually by adding half-one tablet to the daily dose once every week. If you have not had dopamine medications before, the final dose is usually between 2-4mg but if Cabaser is being used with levodopa you may take up to 6mg/day. In addition to these therapeutic effects, Cabaser also causes a reduction in blood pressure.

Low blood pressure (postural hypotension) can occur following administration of this medicine, particularly during the first few days. Care should be taken when taking Cabergoline with other drugs known to lower blood pressure. Care should be taken when taking Cabaser with other drugs known to lower blood pressure.

Following diagnosis of pleural effusion or pulmonaryfibrosis, the discontinuance of DOSTINEX was reported to result in improvementof signs and symptoms. DOSTINEX Tablets are indicatedfor the treatment of hyperprolactinemic disorders, either idiopathic or due to pituitary adenomas. In addition, in case of pronounced central nervous system effects the administration of dopamine antagonist drugs may be advisable. Asymptomatic decreases in blood pressure (20mmHg systolic and 10mmHg diastolic) may occur usually once during the first 3-4 days after child birth. Tell your doctor or pharmacist if you are taking any other medicines, including any medicines, vitamins or supplements that you buy without a prescription from your pharmacy, supermarket or health food shop. The main symptoms are tremor, rigid posture, slow movements and a shuffling, unbalanced walk.

The pharmacodynamic actions of cabergoline not linked to the therapeutic effect relate only to blood pressure decrease. The maximal hypotensive effect of cabergoline as a single dose usually occurs during the first 6 hours after drug intake and is dose-dependent both in terms of maximal decrease and frequency. Serum creatinine measurements can also be used to help in the diagnosis of fibrotic disorder.

If you are due to have an operation or dental treatment, tell the person carrying out the treatment which medicines you are taking. Each time you collect a fresh supply, check to see if the tablets look the same as you have had before. If they are different, discuss this with your pharmacist who will advise you. It can cause dizziness, especially during the first few days of treatment. Cabergoline is considered the best tolerable option for hyperprolactinemia treatment although the newer and less tested quinagolide may offer similarly favourable side effect profile with quicker titration times. Cabaser tablets are intended to be swallowed (whole or half tablets with a full glass of water) and should be taken with food to reduce side effects of nausea or stomach upsets.